IMPACT OF HYPERGLYCEMIA AND GENETIC POLYMORPHISM IN DIABETIC PATIENTS AFFECTED BY COVID-19.

Authors

  • claudionei roessler UNIOESTE
  • Bianca de Lima Piola
  • Israel Gonçalves de Carvalho Filho
  • Léia Carolina Lício Unioeste - Francisco Beltrão

DOI:

https://doi.org/10.48075/aes.v8i1.28264

Abstract

The world is facing one of the worst pandemics today, where around 4.7 million people lost their lives due to COVID-19. However, people with chronic diseases are more susceptible to worsening their clinical condition when affected by the new coronavirus. Patients with Diabetes mellitus (DM) promote a chronic inflammatory state and when affected by COVID-19, they are more prone to changes in the innate immune system, which can even trigger a storm of cytokines that is harmful to the host. Our objective was to address the impact of genetic polymorphism involving ACE 2 and clinical severity in people with hyperglycemia affected by COVID-19. This is a literature review with a qualitative approach, carried out on the PUBMED portal. The following search string was used: Polymorphism genetic, Diabetes, COVID-19, Hyperglycemia and Critical Care. Regarding polymorphism, it was observed that some variations may play a role in influencing the entry of the virus into the host body and others may be a useful tool to predict disease development and treatment against COVID-19.

Published

04-04-2023

How to Cite

ROESSLER, claudionei; PIOLA , B. de L. .; GONÇALVES DE CARVALHO FILHO , I. .; CAROLINA LÍCIO, L. IMPACT OF HYPERGLYCEMIA AND GENETIC POLYMORPHISM IN DIABETIC PATIENTS AFFECTED BY COVID-19. Acta Elit Salutis, [S. l.], v. 8, n. 1, p. 16, 2023. DOI: 10.48075/aes.v8i1.28264. Disponível em: https://saber.unioeste.br/index.php/salutis/article/view/28264. Acesso em: 13 may. 2024.

Issue

Section

Artigos Originais